Computational Simulations for Aortic Coarctation: Representative Results From a Sampling of Patients

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Results of stenting for aortic coarctation.

E stents have been widely used in peripheral and coronary arteries, postsurgical stenosis of the pulmonary arteries, and in the superior vena cava and conduits in congenital heart diseases.1–8 Several reports support the use of balloon-expandable stents for aortic coarctation (AC) in humans.9–13 This study reports the results obtained with stent implantation in young and adult patients with AC....

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Including aortic valve morphology in computational fluid dynamics simulations: initial findings and application to aortic coarctation.

Computational fluid dynamics (CFD) simulations quantifying thoracic aortic flow patterns have not included disturbances from the aortic valve (AoV). 80% of patients with aortic coarctation (CoA) have a bicuspid aortic valve (BAV) which may cause adverse flow patterns contributing to morbidity. Our objectives were to develop a method to account for the AoV in CFD simulations, and quantify its im...

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Computational simulations demonstrate altered wall shear stress in aortic coarctation patients treated by resection with end-to-end anastomosis.

BACKGROUND Atherosclerotic plaque in the descending thoracic aorta (dAo) is related to altered wall shear stress (WSS) for normal patients. Resection with end-to-end anastomosis (RWEA) is the gold standard for coarctation of the aorta (CoA) repair, but may lead to altered WSS indices that contribute to morbidity. METHODS Computational fluid dynamics (CFD) models were created from imaging and ...

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Three Different Imaging Modalities of a Patient with the Aortic Coarctation

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Aortic wall abnormalities in patients with aortic coarctation

Background Aortic coarctation (AC) represents 7% of congenital heart disease. It is a reversible secondary cause of systemic hypertension, however up to 35% of patients remain hypertensive and 18% have cardiovascular complications such as aortic aneurysm, dissection or aortic valve disease. AC is associated with bicuspid aortic valve (BAV) in around 60%, both diseases alter aortic wall distensi...

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ژورنال

عنوان ژورنال: Journal of Biomechanical Engineering

سال: 2011

ISSN: 0148-0731,1528-8951

DOI: 10.1115/1.4004996